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Reproductive Physiology Laboratory

Photo of John F. Odhiambo
John F. Odhiambo
Associate Professor of Reproductive Physiology
Carver Complex Thomas Wing Office A-108
Phone: (256) 372-4168
Email: John.Odhiambo@aamu.edu

 

Research

We study physiologic and genetic regulations of reproductive function in farm animals. Specifically, we are interested in understanding the impact of maternal nutrition and/or stress on offspring health and fecundity in farm animals. Our overarching goal is to develop Dual-purpose with Dual-benefits agricultural animal model for One-Health research.

 

People

Dr. Odhiambo received his MS and PhD in Reproductive Physiology, and BS in Animal and Veterinary Sciences from West Virginia University. He completed his postdoctoral research fellowship at the Center for the Study of Fetal Programming, University of Wyoming, where he studied fetal origins of obesity and metabolic syndrome in ovine models of overnutrition and undernutrition. Prior to his current position, Dr. Odhiambo worked as Assistant and then Associate Professor of Animal Science at Florida A&M University where he developed a forage-based beef cow-calf management program for limited-resource production systems. He also served as faculty advisor for the college Animal Science club.  In 2020, Dr. Odhiambo was credentialled in Effective College Teaching Practices by the Association of College and University Educators (ACUE) and the American Council on Education (ACE).  

Jasmine

Jasmine Eason

Graduate Student

jasmine.eason@bulldogs.aamu.edu

 Samwel

Enam James Samson

Graduate Student

samsonjamesenam@gmail.com

 

Publications

1: Odhiambo JF, Pankey CL, Ghnenis AB, Ford SP. A Review of Maternal Nutrition

during Pregnancy and Impact on the Offspring through Development: Evidence from

Animal Models of Over- and Undernutrition. Int J Environ Res Public Health. 2020

Sep 22;17(18):6926. doi: 10.3390/ijerph17186926. PMID: 32971930; PMCID:

PMC7559343.

2: Serafim TL, Cunha-Oliveira T, Deus CM, Sardão VA, Cardoso IM, Yang S,

Odhiambo JF, Ghnenis AB, Smith AM, Li J, Nathanielsz PW, Ford SP, Oliveira PJ.

Maternal obesity in sheep impairs foetal hepatic mitochondrial respiratory chain

capacity. Eur J Clin Invest. 2021 Feb;51(2):e13375. doi: 10.1111/eci.13375. Epub

2020 Sep 12. PMID: 32780417.

3: Ghnenis AB, Odhiambo JF, Smith AM, Pankey CL, Nathanielsz PW, Ford SP. A

heretical view: rather than a solely placental protective function, placental

11β hydroxysteroid dehydrogenase 2 also provides substrate for fetal peripheral

cortisol synthesis in obese pregnant ewes. J Dev Orig Health Dis. 2021

Feb;12(1):94-100. doi: 10.1017/S2040174420000112. Epub 2020 Mar 10. PMID:32151296           

4: Pankey CL, Walton MW, Odhiambo JF, Smith AM, Ghnenis AB, Nathanielsz PW, Ford

  1. Intergenerational impact of maternal overnutrition and obesity throughout

pregnancy in sheep on metabolic syndrome in grandsons and granddaughters. Domest

Anim Endocrinol. 2017 Jul;60:67-74. doi: 10.1016/j.domaniend.2017.04.002. Epub

2017 Apr 22. PMID: 28527530.

5: Pankey CL, Odhiambo JF, Smith AM, Ford SP. Effects of maternal obesity in an

ovine model on metabolic outcomes in F2 adults and F3 neonates. Domest Anim

Endocrinol. 2021 Jul;76:106628. doi: 10.1016/j.domaniend.2021.106628. Epub 2021

Mar 27. PMID: 33895699; PMCID: PMC8169583.

6: Ghnenis AB, Odhiambo JF, McCormick RJ, Nathanielsz PW, Ford SP. Maternal

obesity in the ewe increases cardiac ventricular expression of glucocorticoid

receptors, proinflammatory cytokines and fibrosis in adult male offspring. PLoS

One. 2017 Dec 21;12(12):e0189977. doi: 10.1371/journal.pone.0189977. PMID:

29267325; PMCID: PMC5739430.

7: Smith AM, Pankey CL, Odhiambo JF, Ghnenis AB, Nathanielsz PW, Ford SP. Rapid

Communication: Reduced maternal nutrition during early- to mid-gestation

elevates newborn lamb plasma cortisol concentrations and eliminates the neonatal

leptin surge. J Anim Sci. 2018 Jun 29;96(7):2640-2645. doi: 10.1093/jas/sky215.

PMID: 29982763; PMCID: PMC6095368.

8: Tuersunjiang N, Odhiambo JF, Shasa DR, Smith AM, Nathanielsz PW, Ford SP.

Maternal obesity programs reduced leptin signaling in the pituitary and altered

GH/IGF1 axis function leading to increased adiposity in adult sheep offspring.

PLoS One. 2017 Aug 3;12(8):e0181795. doi: 10.1371/journal.pone.0181795. PMID:

28771488; PMCID: PMC5542597.

Class Number Class Name Level
FAS 353 Animal Breeding and Genetics Undergraduate
FAS 345 Practicum II Undergraduate
FAS 424 Animal Models in Biomedical Research Undergraduate
FAS 430L Physiology of Reproduction Lab Undergraduate
CV-Odhiambo

Contact Us

Odhiambo Lab at AAMU
Carver Complex Thomas Wing Office A-108
Dr. John F. Odhiambo
Principal Investigator
Associate Professor of Reproductive Physiology
John.Odhiambo@aamu.edu
256-372-4268

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